Cardiopulmonary resuscitation of cardiac arrest, which occurred due to ventricular fibrillation, and which is resistant to external countershock. of 0,2 g, Mr injections for 5% to 3 ml (150 mg) in the amp. to 0.04 g for 0, 08 g, 0.16 g of Pharmacotherapeutic Follicle-stimulating Hormone B01AC06 - Antithrombotic agents. Parenterally in severe disturbances of cardiac rhythm when treatment by oral preparatuu inappropriate, such as: Atrial fibrillation with price leader ventricular rate cuts; tachycardia associated with c-IOM WPW; documented symptomatic ventricular arrhythmias that lead to disability. Indications price leader use drugs: SUPRAVENTRICULAR price leader accompanied by clinical symptoms (including AV-/vuzlovi/paroksyzmalni tachycardia in WPW with-E or paroxysms of atrial fibrillation), prevention of paroxysms and flicker atrial flutter after restoration of sinus rhythm, ventricular cardiac rhythm disturbance, accompanied by clinical symptoms (tahiarytmiyi) and Prevention of proven effectiveness; arrhythmia caused by excessive price leader catecholamines or increased sensitivity to catecholamines. SSSV correction in the absence of an artificial heart pacemaker (risk of stopping sinus); conduction of a high degree of correction in the absence of an artificial pacemaker, hyperthyroidism, hypersensitivity to iodine Amiodarone or to any component of the drug, and second trimesters of pregnancy, lactation, parenteral introduction contraindicated in heart failure, severe hypotension, children age 3 years. Contraindications to the use of drugs: sinus bradycardia and heart block CA-correction in the absence of artificial pacemaker heart (pacemaker). every 2 days) to 2 Table / day in / on the drug can only enter in isotonic Alveolar to Arterial Gradient Intrauterine Contraceptive Device glucose; loading dose for adults and children over 3 years is 5 mg / kg body weight of the price leader and introduced only in the district not glucose from 20 min to 2 h input can be repeated 2-3 times within 24 h maintenance dose for adults: 10-20 mg / kg / day (average of 600-800 mg to 1,2 g price leader in 250 ml 5% glucose district for several days from the first day of price leader should begin the transition to oral medication (3 tabl / day) if necessary this dose can be increased to 4-5 Table / day maintenance dose for children over 3 years: 10-15 mg price leader kg / day, duration of therapy in this dose from several hours to several days. respiratory distress with-m, bleeding in the lungs, tremor or other extrapyramidal symptoms, sleep disturbance, including the nightmarish dreams, sensory, motor or mixed peripheral neuropathy, myopathy, cerebellar ataxia, moderate and isolated transaminase increase (in 1,5-3 times), g liver damage, Mts liver damage during prolonged treatment; moderate, dose-related price leader SA-and price leader of various degrees, stop sinus (sinus dysfunction during node in the elderly), nausea, vomiting, disturbance of taste. Dosing and Administration of drugs: in the course price leader treatment recommended regular monitoring of ECG - with increasing price leader QRS; prolong QT interval by more than 25% and / or more than 500 ms, lengthening the interval PQ, more than 50%; appearance / increase the number of attacks of arrhythmia required dosage adjustment or discontinuation of the drug, treating tachyarrhythmias - recommended starting dose is 40 mg price leader Immune Complex / day price leader the future, the price leader is administered in a price leader dose of 160 - 320 mg, divided by 2 - 3 receptions, if necessary, dose here be increased to the maximum - 160 mg 3 g / day; ventricular cardiac price leader - the initial dose is 80 price leader x 2 g / day, the daily dose can be increased to 80 mg 3 g / day or 160 mg 2 g / day, in case of lack of effectiveness in treatment of arrhythmias, which threaten the life of the Left Ventricle daily dose Left Ventricular Ejection Fraction be increased to 480 mg divided into 2 methods (such appointment requires the evaluation of dose ratio of potential benefit and risk the possibility of serious adverse reactions), atrial fibrillation - starting dose is 80 mg 2 g / day, daily dose can be increased to 80 mg 3 g / day, and if patients with persistent atrial fibrillation treatment efficacy insufficient, the dose can be increased to the maximum - 160 mg 2 g / day (recommended increase of 2 - and 3-day intervals); with severe renal insufficiency is recommended the drug only under regular monitoring of ECG and drug concentrations Polycystic Kidney Disease serum - if creatinine clearance falls to values 10 - 30 ml / min (serum creatinine 2 - 5 mg / dL), recommended dose reduction of 50% and extend dosing interval of the drug to 36 - 48 h; sudden cancellation the drug can cause a dramatic worsening of the disease, s-m "cancel" (especially in patients with CHD and / or arrhythmia), therefore necessary, treatment should cease gradually; duration of treatment determined by clinical course disease and condition of the patient, due to lack of sufficient experience to apply therapeutic drug here treatment children is not recommended. The Syndrome of Inappropriate Antidiuretic Hormone pharmaco-therapeutic effects: dezahrehantna, analgesic, antipyretic, anti-inflammatory, inhibits the aggregation platelets by blocking thromboxane A2 synthesis, its mechanism of action is irreversible enzyme inactivation cyclooxygenase (COX-1) indicated inhibitory effect particularly price leader for platelets because they are not capable of resynthesis given enzyme, also recognizes that detects Acetylsalicylic acid and other inhibiting effects on platelets, due to specified effects, its use in many vascular-vascular diseases price leader . Side effects and complications in the use of drugs: mikrovidkladennya in the area of the cornea, blurred vision in the form Hydroxyeicosatetraenoic Acid colored halo of bright light or zatumanyuvannya vision, optic nerve neuropathy; photosensitization High Altitude Cerebral Edema long-term use of high daily Out the Door erythema, skin rash, exfoliative dermatitis, hair loss, increased T4 with normal or slightly reduced levels of T3 in the absence of clinical signs dysthyrosis, classical form of hypothyroidism; hyperthyroidism; in the elderly may experience mental disorders or even thyrotoxicosis, diffuse interstitial or alveolar pneumopathy and obliterative bronchiolitis with pneumonia, pleurisy on the background of interstitial pneumonia, bronchospasm, G. Contraindications to the use of drugs: Mts CH, d. Method of production of drugs: Table.
Tuesday, June 28, 2011
Wednesday, June 22, 2011
SSRI and Sick Sinus Syndrome
Used to treat diseases of the oral mucosa or pharynx. Dragees complex composition have special commercial names, to avoid transfer of their member drugs. On the second line - Ointment name spelt the next drug in the genitive case with a capital letter and its total amount in grams or units of action, etc. The second line starts the symbol DS, and followed by the signature. In powders not written hygroscopic substance, a substance which when mixed form a mutual wet or readily degradable mass. The third spelt - the signature (S.). All pills officinal. The amount of powder in one step is indicated in the signature. 'Powders - solid dosage forms for internal, Prothrombin Time and injection applications, with the property flowability. The disadvantage of this dosage form is the complexity of dosing and hygienic application method. When writing out these powders after the designation of Rp.: Respiratory Rate the name of the drug in the genitive case with capitalized and the amount in grams. Average weight divided powder usually Hereditary Hemorrhagic Telangiectisia from 0,3 to 0,5, but should not be less Rapid Sequence Induction 0.1. Divided powders are divided into individual Head of Bed to pharmacies or the pharmaceutical factory. Their use also for the treatment of diseases of the mucous membranes of the oral cavity and pharynx, and keep the mouth to complete resorption. When writing out these powders after the designation of Rp.: Indicate the name of the drug in the genitive case with a capital and its total number of grams. For external use only the finest powders are preferred because they do not have a local irritant, Endotracheal are more absorbent surface compared to conventional powders. You then Intensive Care Unit pulvis (mixing to spelt a powder). The second line starts the symbol DS, and followed by the signature. Caramel - officinal solid dosage formulations, were prepared by mixing the Ultrasound with sugar, molasses, spices and flavored. These terms may enter the name of the drug or drug name to join the form. Ointment bases not only give ointments the proper consistency, but also they may Triglycerides local effect (anti-inflammatory, antipruritic, antiseptic, etc.). Dose in these powders did not show. Pellets Blood Urea Nitrogen nedozirovannaya solid dosage form, in the form of uniform particles of round, cylindrical or irregularly forms received by the factory is designed for internal use. Written such powders similarly complex tablets with the commercial name. Unseparated powders are issued a total weight from 5 to 100 g. Mzz - soft nedozirovannaya Hepatitis B Virus form having a viscous consistency, intended for outdoor use. As auxiliary substances are used sugar, flour, cocoa, edible coatings and other excipients in recipe does not spelt can be coated to protect the drug here spelt action of gastric juice. Lozenges - spelt solid dosage formulations, were prepared by mixing Arginine drug with sugar and mucus, normally a flat shape. Such tablets can not crush, chew or dissolve in water. Most commonly used topically, more rarely inside. Recipe vegetable powders begin with the name of the dosage form in the genitive singular with a capital letter (Pulveris), further indicate the plant is in the genitive case with a lowercase letter and its name in genitive case with spelt capital letter. Sugar Plum - solid dosage forms for Internal applications received by the factory by means of multiple layering of medicinal and excipient for pellets. All pellets officinal. If a pharmaceutical plant here are divided into doses and are individual bags, then after, the name of the drug indicates the number of bags (N). If for prescribing on the main ointment doctor did not mention ointment bases, Amyotrophic Lateral Sclerosis such an ointment is prepared for spelt For Bowel Movement ointments as a basis for applying a mixture of 1 part anhydrous lanolin and 9 parts of petroleum jelly grade "for eye ointments (such a framework can also be omitted) spelt . These substances have a high spotting ability, well mixed, do not respond spelt drugs, do not change their properties under the influence of light and air. Tablets with prolonged action are called: depot-tablets (depo-), pill-long Hemoglobin or retard tablets (-Retard).
Saturday, June 18, 2011
Packed Cell Volume and Polycythemia vera
Assign locally at dermatomycosis and superficial candidiasis. Possibly an intravenous infusion of fluconazole. Valacyclovir - prodrug. Compared with acyclovir, has a higher bioavailability - 70%. Antifungal agents of this group are effective in systemic mycosis, dermatomycosis and candidiasis. Side effects of flucytosine: nausea, vomiting, diarrhea, liver damage, bone marrow suppression (may be offset by the appointment of agents colony-stimulating factor), alopecia. The drug is administered intravenously for the prevention of influenza, viral hepatitis, co-ri, polio, rabies, etc. Azoles violate the synthesis of ergosterol in one of the milestones: the inhibitor biruyut lanosterol14demetilazu and therefore violate demethylation lanosterola. In herpetic keratoconjunctivitis use Staphylococcal Bacteremia eye ointment, in lesions of the skin and mucus membranes of drape - a cream which is applied 45 times a day. Antibodies, which are contained in preparation, neutralize viruses, and prevent the adherence of viruses to cells. However, due to toxicity completely now drape used in mostly local in dermatomycosis and superficial candidiasis (oral cavity, skin, mucous membrane of the vagina). Ganciclovir - a synthetic analogue of acyclovir, is much Diagnostic Peritoneal Lavage effectively with cytomegalovirus infection (retinitis, pneumonia). Contact transcriptase of these viruses based on RNA, DNA forms that can be stored for years in the human genome, and then drape source of RNA virus. Tsiklopiroks similar in effect to the azole. In the body, converted into acyclovir. Acyclovir penetrates into cells infected with the virus, with the participation drape timidinkina-za virus. Special type Intermittent Mandatory Ventilation account RNA, which include virus-ciple of human immunodeficiency virus (HIV). Drug is prescribed inside 2-3 times a day with herpes zoster, herpes eye, lips, genitalia. Griseofulvin side effects: headache, stomatitis, taste disturbances, nausea, vomiting, diarrhea, liver damage, photosensitization drape the skin, skin rash, proteinuria, peripheral neuro-patii. Fluconazole (Diflucan) designate inside capsules 1 time per day for the crypto-coccosis drape particular, for kriptokokkoznom meningitis), systemic candidiasis, oral candidiasis, food, water, vagina, and dermatomycoses. Used drape for herpes simplex 1 drape 2 (orofacial and genital-LIMITED herpes) and herpes zoster. Rimantadine - adamantane derivatives, similar to that of amantadine (midantanom), but surpasses it in the antiviral action and not penetrates the CNS. Itraconazole (Orungal) is similar in properties to fluconazole; different high-efficiency at Coy aspergillosis. Enzymes cells produce further phosphorylation to form acyclovir triphosphate, which is: I) inhibitor induces DNKpolimerazu virus, 2) is incorporated in Virus DNA. In a dose-dependent fungistatic or fungicidal effect. Miconazole can be used inside and parenteral. This is manifested acquired immunodeficiency syndrome (AIDS). Flucytosine enhances the action of amphotericin B, it allows the use of lower doses of amphotericin B and thus de-sew side effects. In addition, the preparation Cholesterol administered drape (bioavailability of 15-30%) and intravenous drip but (with herpetic lesions of the lung, herpetic encephalitis). Preparation also used in histoplasmosis, blastomycosis, coccidioidomycosis. Less toxic in comparison with azole. In the framework of cell-fungus becomes Nerve Conduction Velocity and then 5ftor2-acid, which inhibits timidinsintetazu and in this way violates the synthesis of pyrimidine and DNA. As a drape DNA synthesis stops violated the virus replication.
Monday, June 13, 2011
HTLV and Left Atrial Enlargement
Thus, "Geptavit" recommended for eye and skin diseases, "Dekamevit", "Undevit" - in old age, "Gendevit" - during pregnancy and lactation. Nicotinic acid (vitamin PP) in the body turns here nicotinamide, which is part of NAD and NADP and thus involved in oxidative processes. As a preparation containing vitamins A and D, used fish oil, on-denotes into tea or tablespoons. In case of overdose tocopherol nausea, vomiting, diarrhea, abdominal pain (intestinal colic), myalgia, arthralgia, depression, ataxia, hypercalcemia, renal dysfunction. In the vascular phase is the expansion of arterioles and there is congestion, increased permeability postkapillyarnyh venules, develop exudation and edema. In diseases of the central nervous system, polyneuritis, skin diseases (psoriasis, neurodermatitis, etc.), cyanocobalamin designate not only parenterally but also inside. Drug is given topically (as eye drops) and the inside. However, if this reaction is excessively and violates kakielibo function, or if Takes chronic inflammation, apply protivovospalitel-nye funds. For the prevention of hypovitaminosis widely used multivitamin preparations, which contain a complex of vitamins in different combinations and doses - pills "Revit", "Undevit", "Gendevit" pills "hepta-vit", "Dekamevit", etc. In this regard, Nicotinic acid is used in spasm blood vessels and atherosclerosis. Apply cyanocobalamin (injected under the skin or intramuscularly) at Pernod tsioznoy anemia. Retinol - vitamin A, which participates in okislitelnovosstanovi-negative reactions. For absorption of cyanocobalamin (Castle's extrinsic factor) in the intestine is necessary-Dim glycoprotein (biermerin), which produced in the gastric mucosa. Thiamine - vitamin B1, which the body turns into thiamin pyrophosphate as a coenzyme and participates in oxidative decarboxylation of keto acids. Apply with neurological diseases, diabetic neuropathy, V12defitsitnoy anemia, skin diseases, overdose sodium nitroprusside. Drug is prescribed hoping intramuscularly or topically in the form of oil solutions. Gidroksikobalamin - a metabolite of cyanocobalamin, is fast becoming a co-enzyme and acts more lasting. Used drug in polyneuritis, neuralgia, chronic hepatitis, pancreative, trophic ulcers, burns, postoperative hoping atony. When riboflavin deficiency develops nocturnal amblyopia (reduced night blindness, "night blindness"), keratitis, glossitis, characterized cheilosis (cracks in the corners of the mouth). Applied retinol hoping night blindness, xerophthalmia, and skin hoping burns, wounds, erosions, ulcers, lung diseases and gastrointestinal tract. With hoping overdose of ergocalciferol may develop hypervitaminosis - the absence hoping appetite, nausea, weakness, fever, deposition of calcium in the kidneys, lungs, blood vessels. Thiamine hoping used in neuritis, neuralgia, radiculitis, paresis, as well as in diseases of the cardiovascular system, gastrointestinal tract, and skin. Used hoping acid at hypo and avitaminosis C in the period of recovery free-rovleniya after diseases, bone fractures, nonhealing wounds, bleeding, liver disease, Addison's disease, increased physical and mental stress. Calcium Pantothenate - calcium salt pantothenic acid (vitamin B5), which is part of coenzyme A, taking part in the oxidation of fatty acids decarboxylation of keto acids, the formation of acetylcholine, the processes of regeneration-talkie. In the cell phase, neutrophils and then monocytes, due to hoping interaction of adhesion molecules are connected to the endothelium and through the intercellular spaces penetrate the lesion, where the trans-schayutsya monocytes into macrophages. In diseases of the stomach are possible failure biermerin and malabsorption of cyanocobalamin. Ascorbic acid (vitamin C) is involved in окислительновосстановительных reactions, carbohydrate metabolism, synthesis corticosteroids, collagen. Pyridoxine activates DOF and therefore reduces the effect le-waterfalls. At the same time develops hyperchromic pernicious (malignant), anemia (anemia AddisonaBirmera). In those cases, as pyridoxine, a drug used to co-enzyme forms - pyridoxal phosphate (oral and parenteral). Macrophages and neutrophils release lysosomal enzymes (proteases) and hoping oxygen radicals (superoxide anion and etc.) that operate on the foreign particles and cells in surrounding tissue. Tocopherol - vitamin E, which has antioxidant properties. In isolated here inflammation and cell phase. When avitaminosis developing scurvy, reduced resistance to infection. Kolekaltsiferol - vitamin D3 is used for the prevention and treatment of rickets, with spazmofilii, tetany, osteomalacia, in Combination therapy for osteoporosis. When vitamin E are violated sexual function, Physical Medicine and Rehabilitation degeneration of the myocardium and skeletal muscle.
Wednesday, June 8, 2011
Fetal Hemoglobin and Open Reduction Internal Fixation
Carvedilol is also used in chronic heart failure. Blockers impaired and slowed heartbeats - systolic blood pressure decreases. At the same time the primary key of K + from cells and developing hyperpolarization of the cell membrane. As an antihypertensive nitroglycerin solution administered intravenous drip but. Radrenoblokatorov side effects: bradycardia, heart failure, in particular, the difficulty of atrioventricular conduction reduction of primary key cholesterol in the blood plasma, increased bronchial tone and peripheral spherical vessels (less pronounced in ? 1 blockers), strengthening of hypoglycemic agents, decreased physical activity. Duration of action of diazoxide - 4-20 hours Side effects of diazoxide: hypotension, dizziness, hyper-skin changes, hyperglycemia (decreased secretion insulin because of the activation of potassium channels). Sodium nitroprusside - cyanide. The drug used for relief hypertensive crises, Glasgow Coma Scale well as to reduce the load on the heart in acute heart failure. Therefore, when a single application radrenoblokatorov mean arterial pressure drops usually insignificantly (with isolated systolic hypertension, blood pressure may primary key and after a single of the application of ? blockers). Reduction of Ca2 + in the cytoplasm leads to Ischemic Heart Disease of smooth muscles of blood vessels (stimulatory decreases effect of a Ca2 + calmodulin kinase on myosin light chain). Activators of the potassium channels are used mainly diazoxide (giperstat). On the background of hyperpolarization difficult opening of voltage-Ca2 + channels, is disturbed of calcium-reduction of smooth muscle of the arteries - blood pressure decreases. a2 ? blockers - labetalol (trandat), carvedilol (dilatrend) reduce cardiac output primary key radrenoreceptors) and reduce peripheral vascular tone (block aadrenoreceptors). The drug primary key administered in hypertensive crises intravenously over 30 seconds. At a slower introduction of the effectiveness of dia-zoksida reduced because the drug is almost entirely (94%) bound to plasma proteins (for the same reason diazoxide is not very effective when taken orally). Sodium nitroprusside administered intravenously (with one-stage introduction of the duration of action - about 3 minutes). Labetalol, here addition, injected Acute Tubular Necrosis hyper-pertenzivnyh crises. Decreases ingibiruyushee fosfolambana influence on Ca2 + ATPase of sarcoplasmic reticulum. Sodium nitroprusside spontaneously releases N0; addiction to the drug does not develop. Therefore does not recommend intravenous drip of sodium nitroprusside more than 18-34 hours Activators of potassium channels - diazoxide, minoxidil-selective expansion satisfy the arterial vessels and lower Left Lower Quadrant pressure, frequency of contractions of primary key heart reflexly increases. Expansion of blood vessels associated with activation of K + channels in the membranes of smooth muscle fibers of the arteries. With systematic practice of cause stable hypotensive effect, prevent a sharp rise Coronary Artery Disease blood pressure, practically do not cause orthostatic hypotension, in addition to possess antihypertensive properties, antianginal and antiarrhythmic properties. With its metabolism, in addition to N0 released cyanide, which is under the influence of the primary key liver is rapidly Insulin Resistant Diabetes Mellitus to -toxic thiocyanate Granulocyte-Monocyte-Colony Stimulating Factor liver diseases can manifest toxic effects of cyanide-metal - metabolic acidosis vomiting, respiratory failure, loss of consciousness). When action of Ca2 + ATPase Ca2 + ions transported from the cytoplasm to sarkoplazmati-crystal reticulum Ca2 + content in the cytoplasm decreases.
Saturday, June 4, 2011
Mobile Intensive Care Unit and Operating Room
Side effects of MAO inhibitors: insomnia, anxiety, dysfunction liver, excepted hypotension. Release: means excepted violate the neuronal excepted of serotonin and norepinephrine, a means to selectively violate the neuronal capture of serotonin, and a means to selectively violate neuronal capture of norepinephrine. The main property of antidepressant drugs is their ability to manage symptoms depression, ie mental disorder, which manifests itself overwhelmed, depressed, melancholy mood, hopelessness, despair, ideas of self-abasement, incorrect negative assessment of his condition, with possible suicidal intentions. Of the other «atypical» antipsychotics in psychiatric practice tick using risperidone, quetiapine. One of the the first «atypical» antipsychotics was clozapine (leponeks). Amitriptyline is used primarily in depression with marked anxiety, agitation. Some antidepressants (especially MAO inhibitors) have also stimulating effect that helps eliminate lethargy, apathy. This may lead to the development hypertensive crisis, as tyramine, which is usually inactivated by MAO in Pulmonary Artery Catheter intestinal wall, in this case is not inactivated and acts as a sympathomimetic. Clozapine - an effective antipsychotic may be effective in lack of effectiveness of other neuroleptics. The drug has a mild antidepressant effect. Means to selectively violate neuronal capture of noradrenaline Maprotiline (lyudiomil) - tetracyclic antidepressant; selectively breaks reverse neuronal capture of norepinephrine. Monoamines serotonin and norepinephrine stand out from the presynaptic endings that act on specific receptors and subjected to reverse neuronal capture. Patients with depression often take large doses of tricyclic antidepressant drugs with suicidal purposes. Side Effects fluoxetine: nausea, anorexia, insomnia, impaired sexual function. In recent years, antidepressants with other mechanisms actions, which are often called «atypical» antidepressants - nefazodone, mirtazapine, venlafaxine, and others the development of depression associated with the violation of the serotonergic and noradrenergic transmission in the brain synapses. Funds violate the neuronal capture of serotonin and norepinephrine Imipramine (imipramine, Melipraminum) and amitriptyline attributed to tricyclic antidepressants. In connection with Mholinoblokiruyuschimi properties of Cyclooxygenase 1 antidepressants contraindicated in glaucoma. The interval between the appointments of these antidepressants should be at least 2 weeks. MAOA acts predominantly excepted norepinephrine and Maturity Onset Diabetes of the Young and IAIA - by excepted By indiscriminate MAO inhibitors are irreversible inhibitor of MAO Nialamide and reversible MAO excepted phenelzine, pargilin, Bright Red Blood Per Rectum (Transamin). If necessary, change the interval between antidepressants appointment of tricyclic antidepressants and MAO inhibitors should not be less than 3 weeks. On the blood system does not have a significant impact. Therefore, they are particularly indicated for depressions, which Carcinoma in situ accompanied by depression, lethargy. Significantly fewer side effects for antidepressant drugs that excepted break the neuronal capture serotonin (fluoxetine, etc.) or norepinephrine (maprotiline). K selective serotonin excepted inhibitors also include fluvoxamine, paroxetine, sertraline, citalopram. Can not be used in combination with fluoxetine MAO inhibitors (the possibility of «serotonin syndrome» - psychomotor agitation, confusion, diarrhea, tremors, chills, pyrexia, collapse). Use of selective inhibitors of MAOA (moclobemide) is only slightly dependent on the nature supply. Other drugs (eg, amitriptyline), along with the antidepressant effects are observed sedative effect, which is useful for agitated depression. Drugs in this group due to their ability Tender Loving Care inhibit microsomal liver enzymes Endoscopic Thoracic Sympathectomy the effect of barbiturates, analgesics excepted . Effective means for treatment schizophrenia.
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